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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A5
All Species:
16.67
Human Site:
S54
Identified Species:
33.33
UniProt:
Q9H2X9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2X9
NP_001128243.1
1139
126184
S54
E
S
S
P
F
I
N
S
T
D
T
E
K
G
K
Chimpanzee
Pan troglodytes
XP_001173480
1150
127612
N119
A
R
N
A
Y
L
N
N
S
N
Y
E
E
G
D
Rhesus Macaque
Macaca mulatta
XP_001104798
1116
123517
E51
N
M
A
L
F
E
E
E
M
D
T
S
P
M
V
Dog
Lupus familis
XP_543029
1042
114973
Y40
D
T
E
K
G
R
E
Y
D
G
K
N
M
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91V14
1138
126252
S54
E
S
S
P
F
I
N
S
T
D
T
E
K
G
R
Rat
Rattus norvegicus
Q63633
1139
126228
S54
E
S
S
P
F
I
N
S
T
D
T
E
K
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506148
1141
126778
S72
E
S
S
P
F
I
H
S
P
E
M
E
R
E
N
Chicken
Gallus gallus
NP_001006371
1125
125222
S52
E
S
S
P
F
I
N
S
A
E
M
D
R
G
N
Frog
Xenopus laevis
Q0VGW6
899
98326
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
A18
V
G
E
D
G
I
P
A
D
Y
K
G
N
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
P55
K
V
S
S
K
Y
D
P
D
N
P
N
K
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
96.1
88
N.A.
98.2
98.2
N.A.
72.1
73
24.6
25.2
N.A.
N.A.
N.A.
35.9
N.A.
Protein Similarity:
100
81
97
89.1
N.A.
98.6
98.8
N.A.
82.9
83.9
42.7
43.1
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
100
20
20
0
N.A.
93.3
93.3
N.A.
53.3
60
0
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
66.6
26.6
13.3
N.A.
100
100
N.A.
73.3
80
0
0
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
9
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
9
0
25
34
0
9
0
9
9
% D
% Glu:
42
0
17
0
0
9
17
9
0
17
0
42
9
9
0
% E
% Phe:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
17
0
0
0
0
9
0
9
0
42
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
9
9
0
0
0
0
0
17
0
34
0
25
% K
% Leu:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% L
% Met:
0
9
0
0
0
0
0
0
9
0
17
0
9
9
0
% M
% Asn:
9
0
9
0
0
0
42
9
0
17
0
17
9
0
17
% N
% Pro:
0
0
0
42
0
0
9
9
9
0
9
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
9
0
0
0
0
0
0
17
9
17
% R
% Ser:
0
42
50
9
0
0
0
42
9
0
0
9
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
25
0
34
0
0
0
0
% T
% Val:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
9
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _